Total Knee Replacement: Are there any alternatives- Dr Siddharth Shah

By / 3 months ago / Doctors Speak / 27 Comments
Total Knee Replacement: Are there any alternatives- Dr Siddharth Shah

Millions of Indians suffer from Knee Osteoarthritis (OA) which adversely affects their quality of life. Its prevalence in India is estimated to be nearly 29% (Pal et al, Indian Journal of Orthopaedics, 2016). OA is characterized by joint degeneration commonly due to wear and tear. Initial management generally involves activity modification (avoidance of squatting, cross-legged sitting etc.), weight management, regular healthy exercise, muscle strengthening Physiotherapy, and pain-relieving medications. Additional treatment is required if symptoms are not adequately controlled by the above measures. It is common knowledge that advanced cases of knee OA can be managed by total Knee Replacement (TKR). However, awareness about other treatment options for knee OA is extremely limited. Alternatives to TKR for knee OA include biological & regenerative treatments, partial knee replacement (PKR), and leg realignment surgery.

Biological & Regenerative Treatments: These are novel, non-surgical treatment options for knee OA. Substances which are naturally found in the human body are used to facilitate healing of a worn-out joint. They help relieve symptoms and reduce or avoid the use of pain-killers altogether. Due to their biological nature, these treatments are generally considered safe. The following treatments have demonstrated beneficial effects in patients with knee OA.

Platelet Rich Plasma (PRP): Platelet cells normally present in human blood are packed with growth factors. They can help reduce inflammation and promote healing of an arthritic joint. PRP is prepared by withdrawing a small amount of patient’s own blood and centrifuging it. A carefully separated portion of the centrifuged material which has a high concentration of platelets is injected into the arthritic knee joint. Scientific literature shows that PRP injection improves symptoms of knee OA and can help delay surgery (TKR).

Bone Marrow Aspirate Concentrate (BMAC): BMAC is prepared by extracting Bone Marrow from patient’s pelvic bone using a special needle. A centrifuged fraction rich in Stem Cells is injected into the arthritic joint. Stem cells can transform into different tissues including Cartilage, and have regenerative potential. Researches shows that BMAC injections help improve pain and activity levels in patients suffering from knee OA.

Hyaluronic Acid (HA): Synovial Fluid naturally present in the knee joint provides lubrication, nourishment and acts as a shock absorber. HA is an essential component of normal synovial fluid. The quality of HA deteriorates in knee OA which affects synovial fluid function resulting in symptoms. HA injection can help improve the quality of knee joint fluid and thus relieve symptoms. 

Autologous Protein Solution (APS): This utilises a fraction of patient’s own blood which is rich in anti-inflammatory substances and growth factors. It counteracts the ongoing process of cartilage damage and promotes healing in the joint. Evidence shows that APS injection helps relieve pain, stiffness, and aid function in patients suffering from knee OA.

Partial knee replacement (PKR): PKR simply means replacing only the damaged portion of the knee as against TKR, which involves replacing the entire knee joint. Thus, the rest of your healthy knee joint is preserved. PKR is minimally invasive with a smaller incision and usually results in lesser pain. It is a muscle, ligament and bone preserving procedure which allows quicker recovery. Patients frequently state that the knee feels more natural and may also bend better as compared to TKR. They are often more satisfied and return to normal activities faster. It is particularly suitable for those who want to return to an active lifestyle.

Leg Realignment Surgery (Osteotomy): Realignment surgery involves controlled alteration of the patient’s leg alignment in order to transfer body weight from the arthritic part to the healthy normal part of the knee. Consequently, reduced loading of the arthritic part helps relieve patient’s symptoms and can avoid knee replacement surgery.

While choosing a treatment for your knee arthritis, discuss all possible alternatives with your surgeon in order to select the best treatment suited to your lifestyle and needs.

Sahil Saini

Sahil Saini

The author didn't add any Information to his profile yet.


  • realizare website17. Jan, 2020

    I read this post fully about the difference of latest and previous
    technologies, it’s awesome article.

  • Waynedaf17. Jan, 2020

    Cialis cialis 20 mg best price cialis prices

  • Jan, 2020

    Hello there! This is kind of off topic but I need some advice from
    an established blog. Is it tough to set up your own blog?
    I’m not very techincal but I can figure things out pretty fast.
    I’m thinking about creating my own but I’m not sure where to start.
    Do you have any ideas or suggestions? Appreciate it

  • Jan, 2020

    Remarkable! Its actually remarkable paragraph, I have got much clear idea regarding from this

  • Jan, 2020

    Very rapidly this website will be famous amid all blog visitors, due to it’s nice articles

  • sling tv14. Jan, 2020

    Hi there! I know this is somewhat off topic but I was wondering
    which blog platform are you using for this website? I’m getting tired of WordPress because I’ve
    had issues with hackers and I’m looking at options for another platform.
    I would be awesome if you could point me in the direction of
    a good platform.

  • Peterwal13. Jan, 2020

    Hello, reprimand you in spite of word! price of cialis
    viagra erection

  • EverettJag09. Jan, 2020

    Hello, thank you for word! cost of viagra 100mg I repost in Facebook.
    viagra without a doctor prescription

  • sling tv asksylphoflight.tumblr.com07. Jan, 2020

    Have you ever thought about including a little bit more than just your articles?
    I mean, what you say is important and everything. However just imagine
    if you added some great images or videos to give your posts more, “pop”!

    Your content is excellent but with images and videos, this website could undeniably be one of the
    most beneficial in its niche. Wonderful blog!

  • xbody05. Jan, 2020

    Hey just wanted to give you a quick heads up. The words in your content seem to be running off the screen in Chrome.

    I’m not sure if this is a format issue or something to do with
    browser compatibility but I figured I’d post to let you know.
    The design and style look great though! Hope you get the problem fixed soon. Cheers

  • xbody05. Jan, 2020

    Excellent post. I will be dealing with a few of these issues as well..

  • xbody bucuresti05. Jan, 2020

    Having read this I believed it was extremely informative.
    I appreciate you finding the time and effort to put this information together.
    I once again find myself personally spending a significant amount of time both reading and leaving comments.
    But so what, it was still worth it!

  • xbody bucuresti05. Jan, 2020

    Awesome post.

  • online cialis03. Jan, 2020

    Hello, recognition you for information! I repost in Facebook

  • free trial30. Dec, 2019

    I’ve learn a few good stuff here. Definitely price bookmarking for revisiting.

    I surprise how so much attempt you place to create the sort of wonderful informative web site.

  • free trial29. Dec, 2019

    Thank you, I have recently been looking for
    information approximately this topic for ages and yours is the greatest I’ve
    came upon so far. However, what concerning the
    bottom line? Are you sure in regards to the source?

  • servicii web design24. Dec, 2019

    Hey there! I just wanted to ask if you ever have any trouble with hackers?
    My last blog (wordpress) was hacked and I ended up losing a few months of hard
    work due to no backup. Do you have any methods to prevent hackers?

  • web design bucuresti24. Dec, 2019

    I think the admin of this web site is actually working hard in favor of his web site, as here every stuff is quality based material.

  • servicii web design24. Dec, 2019

    I read this piece of writing fully concerning the resemblance of
    hottest and preceding technologies, it’s remarkable article.

  • coconut oil20. Dec, 2019

    Hello, all is going fine here and ofcourse every one is sharing information, that’s actually excellent,
    keep up writing.

  • coconut oil16. Dec, 2019

    I do believe all the ideas you’ve presented on your post.

    They’re very convincing and can certainly work.
    Nonetheless, the posts are very brief for newbies.
    Could you please lengthen them a little from subsequent time?

    Thank you for the post.

  • ps4 games12. Dec, 2019

    I’ve learn several just right stuff here. Definitely
    value bookmarking for revisiting. I surprise how a lot attempt you put to make this kind of great informative site.

  • quest bars cheap09. Dec, 2019

    For the reason that the admin of this site is working, no doubt very quickly it will be well-known, due to its quality contents.

  • quest bars cheap coupon twitter03. Dec, 2019

    you’re in point of fact a good webmaster. The
    website loading velocity is incredible. It sort of feels that you’re doing
    any distinctive trick. Furthermore, The contents are masterpiece.
    you’ve done a great task in this subject!

  • quest bars cheap coupon twitter02. Dec, 2019

    I’m not that much of a internet reader to be honest but
    your blogs really nice, keep it up! I’ll go ahead
    and bookmark your website to come back later on. Cheers

  • wormateio gameplay02. Dec, 2019

    Your means of telling all in this article is genuinely pleasant,
    all be able to effortlessly know it, Thanks a lot.

  • plenty of fish dating site26. Nov, 2019

    I got this web page from my buddy who told me regarding this web page and now this time I am browsing this
    web page and reading very informative articles or reviews at
    this place.

Leave a comment

Your email address will not be published. Required fields are marked. *